This Practice Advisory provides an overview of the currently available COVID-19 vaccines and guidance for their use in pregnant, recently pregnant, lactating, and nonpregnant individuals aged 12 years and older. For guidance and recommendations for the use of these vaccines in individuals aged 11 years or younger, please visit the website of the American Academy of Pediatrics. For additional information regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and treatment, see ACOG’s Frequently Asked Questions.

This Practice Advisory has been updated to include the following:

• Preferential recommendation for the mRNA COVID-19 vaccines over the Johnson & Johnson/Janssen (J&J/Janssen) COVID-19 vaccine for the primary series and booster vaccination, including for persons who are pregnant or lactating
• Updated data on thrombosis with thrombocytopenia syndrome following J&J/Janssen COVID-19 vaccination
• New data further supporting the safety and efficacy of COVID-19 vaccination during pregnancy
• Recommendations regarding the timing of booster doses in pregnant and nonpregnant individuals for mRNA and J&J/Janssen vaccines